Black tiger shrimp (Penaeus monodon) is a comprehensive decapod crustaceans raised for human consumption. Currently, the virus from two different lineages of parvovirus (PV, family Parvoviridae; subfamily Hamaparvovirinae) infects penaeid shrimp.

Here, the PV was isolated and cloned from Vietnam specimens of P. monodon, Penaeus monodon appointed metallodensovirus (PmMDV). This was the first member of a different lineage third proved to infect penaeid decapods. PmMDV has the unique transcription strategy among PV invertebrates, extensive use of alternative splicing and transcription incorporating elements characteristic of PV-infect vertebrates. The PmMDV protein has no significant sequence similarity with other PV, except for the helicase domain SF3 its nonstructural protein.

The capsid structure, determined by cryoelectron microscope for 3-Å resolution, has a surface morphology similar to Penaeus stylirostris densovirus, despite the lack of significant capsid viral proteins (VP) of sequence similarity. Unlike other PV, VP crease PmMDV without combining βA multimer strand and shown a unique interaction, including the incorporation of cations Ca2 +, attach the N termini below fivefold icosahedral symmetry axis and forming a basket-like pentamer helix bundle. While the order PmMDV VP does not have a canonical domain of phospholipase A2, the structure of a capsid EDTA-treated, determined to 2.8-Å resolution, suggesting a mechanism cation-dependent membrane-penetrating alternative in the N-terminal region.

PmMDV is observed examples of convergent evolution between invertebrates PV capsid structure in connection with the host-driven and unique as PV shows the structure of the cation-sensitive cart / egress endosomal depending on the alternative. Bioinformatics is a very resourceful tool for understanding the evolution of membrane proteins, such as transient receptor potential channel. bioinformatics expert users rely on special scripting and programming skills. Some web servers and standalone tools are available to users nonadvanced is willing to develop projects to understand their system of choice.

molecular biology and evolution of cancer: from discovery to action.

Cancer development is an evolutionary process. During this process, the growing population of cancer cells undergo limit the ecological niches in the body, such as primary tumor, circulatory system, and metastatic sites vary. heterogeneous population of cancer cells undergo selection for adaptive phenotypes, which form the molecular genetic variations in the same genetic drift. cell lineage underwent convergent evolution towards a phenotype known as hallmarks of cancer that promote cancer initiation, growth, and metastasis.

Efforts to prevent or delay cancer evolution-and-development requires a deep understanding of the underlying process of molecular evolution. Here we discuss the suite concept and tools of the theory of evolution and ecology that can inform-and possibly change-cancer biology in new ways and means. These concepts and tools including comparative research on cancer throughout the different species and the application of phylogenetic approaches to analyze the evolution of tumor progression and metastasis.

Tetrahydrofuran, GlenDry™, anhydrous over molecular sieve
GS8667-2500	Glentham Life Sciences	2500	EUR 246.9

Tetrahydrofuran, GlenDry™, anhydrous over molecular sieve
GS8667-500	Glentham Life Sciences	500	EUR 104.1

Tetrahydrofuran (THF)
TC8900	Bio Basic	1L	EUR 103.85

Magnesium Acetate Tetrahydrate for molecular biology, 99%
50488	Sisco Laboratories	100 Gms	EUR 2.74
Description: Part A

Tetrahydrofuran (THF) for HPLC & UV Spectroscopy, 99.9%
94842	Sisco Laboratories	500 ml	EUR 6.71
Description: Part A

Tetrahydrofuran (THF) GC-HS, 99.9%
32661	Sisco Laboratories	250 ml	EUR 4.11
Description: Part A

Tetrahydrofuran (THF) (Stabilized) pure, 99.5%
82863	Sisco Laboratories	500 ml	EUR 4.52
Description: Part A

Magnesium acetate - Tetrahydrate (Molecular Biology Grade)
CE190	GeneOn	500 g	EUR 98.4

Tetrahydrofuran (THF) Dried, 99.5%, 0.005% water
59167	Sisco Laboratories	500 ml	EUR 6.5
Description: Part A

Tetrahydrofuran (THF) (Stabilized) extrapure AR, 99.5%
74497	Sisco Laboratories	500 ml	EUR 4.79
Description: Part A

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)
HY-109521A	MedChemExpress	5 g	EUR 43.29
Description: Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetrahydrofuran-d8 (THF-d8) for NMR spectroscopy, 99.5 Atom %D
22698	Sisco Laboratories	5 ml	EUR 133.42
Description: Part A

Tetrahydrofuran Mix (THF) - 3 pack of 1.5mL ampules - 1.5ML
ECS-B-047	Scientific Laboratory Supplies	1.5ML	EUR 121.5

Tetrahydrofuran (THF) (Stabilized) extrapure AR, ACS, ExiPlus, Multi-Compendial, 99.5%
83642	Sisco Laboratories	500 ml	EUR 5.2
Description: Part A

EDTA Tetrasodium Salt Dihydrate for molecular biology, 99.5%
45247	Sisco Laboratories	100 Gms	EUR 6.16
Description: Part A

Tetrahydrofuran
33112-75	NACALAI TESQUE	500ML	EUR 11.69

Tetrahydrofuran
33113-36	NACALAI TESQUE	100ML	EUR 9.1

Tetrahydrofuran
33113-65	NACALAI TESQUE	500ML	EUR 13.09

Tetrahydrofuran
33116-35	NACALAI TESQUE	500ML	EUR 29.05

Tetrahydrofuran
33125-31	NACALAI TESQUE	1L	EUR 44.1

Tetrahydrofuran
33139-45	NACALAI TESQUE	500ML	EUR 63

Tetrahydrofuran
GK1522	Glentham Life Sciences	500ml	EUR 65.14

Tetrahydrofuran
GK1522-1	Glentham Life Sciences	1	EUR 39.4

Tetrahydrofuran
GK1522-1L	Glentham Life Sciences	1 l	EUR 84

Tetrahydrofuran
GK1522-2500	Glentham Life Sciences	2500	EUR 71.1

Tetrahydrofuran
GK1522-2500ML	Glentham Life Sciences	2500 ml	EUR 122.4

Tetrahydrofuran
GK1522-500	Glentham Life Sciences	500	EUR 23.8

Tetrahydrofuran
T293518	Toronto Research Chemicals	1l	EUR 57
Description: 109-99-9

Casein, for Molecular Biology
MB279-100G	EWC Diagnostics	1 unit	EUR 110.77
Description: Casein, for Molecular Biology

Casein, for Molecular Biology
MB279-500G	EWC Diagnostics	1 unit	EUR 387.65
Description: Casein, for Molecular Biology

Sucrose for molecular biology
27580	Sisco Laboratories	500 Gms	EUR 4.11
Description: Part A

Tetrahydrofuran, 99.9%, for analysis, unstabilised
GK0126	Glentham Life Sciences	1l	EUR 159.23

Tetrahydrofuran, 99.9%, for analysis, unstabilised
GK0126-1	Glentham Life Sciences	1	EUR 83.1

Tetrahydrofuran, 99.9%, for analysis, unstabilised
GK0126-1L	Glentham Life Sciences	1 l	EUR 136.8

Tetrahydrofuran, 99.9%, for analysis, unstabilised
GK0126-2500	Glentham Life Sciences	2500	EUR 174

Tetrahydrofuran, 99.9%, for analysis, unstabilised
GK0126-2500ML	Glentham Life Sciences	2500 ml	EUR 246

Tetrahydrofuran 99%
T04810	Pfaltz & Bauer	1L	EUR 238.6

Urea for molecular biology, 99.5%
21113	Sisco Laboratories	500 Gms	EUR 6.5
Description: Part A

Tetrahydrofuran - 1ML
S-3460	Scientific Laboratory Supplies	1ML	EUR 51.3

Tetrahydrofuran-d8
T293512	Toronto Research Chemicals	1g	EUR 230
Description: 1693-74-9

Xylene for molecular biology, 99.5%
45122	Sisco Laboratories	250 ml	EUR 2.81
Description: Part A

Tetrahydrofuran-2,2,5,5-d4
T293519	Toronto Research Chemicals	10mg	EUR 64
Description: 20665-63-8

Acetone for molecular biology, 99.8%
27498	Sisco Laboratories	500 ml	EUR 3.76
Description: Part A

Glycine for molecular biology, 99.5%
64072	Sisco Laboratories	100 Gms	EUR 1.64
Description: Part A

Carbinol for molecular biology, 99.5%
34883	Sisco Laboratories	500 ml	EUR 6.23
Description: Part A

Methanol for molecular biology, 99.5%
96446	Sisco Laboratories	500 ml	EUR 6.23
Description: Part A

Formamide for molecular biology, 99.5%
30349	Sisco Laboratories	500 ml	EUR 5.82
Description: Part A

Imidazole for molecular biology, 99.5%
61510	Sisco Laboratories	25 Gms	EUR 5.47
Description: Part A

Chloroform for molecular biology, 99.8%
96764	Sisco Laboratories	100 ml	EUR 3.08
Description: Part A

Urea, suitable for molecular biology
GE1210	Glentham Life Sciences	500g	EUR 53.1

Urea, suitable for molecular biology
GE1210-1	Glentham Life Sciences	1	EUR 58

Urea, suitable for molecular biology
GE1210-1KG	Glentham Life Sciences	1 kg	EUR 106.8

Urea, suitable for molecular biology
GE1210-500	Glentham Life Sciences	500	EUR 33.1

Urea, suitable for molecular biology
GE1210-500G	Glentham Life Sciences	500 g	EUR 76.8

Tetrahydrofuran, GlenUltra™, analytical grade, for LC
GS2560	Glentham Life Sciences	1l	EUR 281.92

Tetrahydrofuran, GlenUltra™, analytical grade, for LC
GS2560-1	Glentham Life Sciences	1	EUR 176.2

Tetrahydrofuran, GlenUltra™, analytical grade, for LC
GS2560-2500	Glentham Life Sciences	2500	EUR 294

Triethylamine for molecular biology, 99.5%
55221	Sisco Laboratories	500 ml	EUR 4.11
Description: Part A

(S)-Tetrahydrofuran-3-ol
HY-76476	MedChemExpress	10 g	EUR 54.11
Description: (S)-tetrahydrofuran-3-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetrahydrofuran-d8 - 1ML
S-3461	Scientific Laboratory Supplies	1ML	EUR 94.5

Ficoll 400® for molecular biology
45460	Sisco Laboratories	5 Gms	EUR 15.6
Description: Part B

Agarose UltraPhor for molecular biology
27813	Sisco Laboratories	10 Gms	EUR 46.5
Description: Part B

Nitro Blue Tetrazolium Chloride (Nitro BT) (NBT) for molecular biology, 99%
48898	Sisco Laboratories	100 Mg	EUR 6.6
Description: Part B

Tetrahydrofuran 〈H2O<50ppm〉
04113-81	NACALAI TESQUE	1L	EUR 64.4

Tetrahydrofuran 〈H2O<50ppm〉
04113-94	NACALAI TESQUE	100ML	EUR 14.7

Boric Acid for molecular biology, 99.5%
22311	Sisco Laboratories	250 Gms	EUR 4.04
Description: Part A

2-Methyl Tetrahydrofuran
24707-100	Polysciences Europe GmbH	100g	EUR 55
Description: 96-47-9

2-Mercaptoethanol ?For Molecular Biology
MB041-100ML	EWC Diagnostics	1 unit	EUR 9.02
Description: 2-Mercaptoethanol ?For Molecular Biology

2-Mercaptoethanol ?For Molecular Biology
MB041-500ML	EWC Diagnostics	1 unit	EUR 26.47
Description: 2-Mercaptoethanol ?For Molecular Biology

ACES Buffer for molecular biology, 99.5%
27907	Sisco Laboratories	5 Gms	EUR 5.4
Description: Part B

Triton X-100 for molecular biology
64518	Sisco Laboratories	100 ml	EUR 6.02
Description: Part A

MOPS Buffer for molecular biology, 99%
66043	Sisco Laboratories	25 Gms	EUR 10.28
Description: Part B

Vitamin B12 for molecular biology, 97%
77472	Sisco Laboratories	250 Mg	EUR 5.78
Description: Part B

NADPH - Tetrasodium salt (Molecular Biology Grade)
CE202	GeneOn	25 mg	EUR 70.8

NADPH - Tetrasodium salt (Molecular Biology Grade)
CE203	GeneOn	100 mg	EUR 126

NADPH - Tetrasodium salt (Molecular Biology Grade)
CE204	GeneOn	500 mg	EUR 374.4

HEPES Buffer for molecular biology, 99.5%
16826	Sisco Laboratories	25 Gms	EUR 6.3
Description: Part B

Sodium Azide for molecular biology, 99%
17782	Sisco Laboratories	100 Gms	EUR 5.47
Description: Part A

CHAPS Buffer for molecular biology, 99.5%
21420	Sisco Laboratories	1 Gms	EUR 10.73
Description: Part B

Agarose Low EEO for molecular biology
36601	Sisco Laboratories	10 Gms	EUR 5.1
Description: Part B

PIPES Buffer for molecular biology, 99%
49159	Sisco Laboratories	100 Gms	EUR 26.03
Description: Part B

10X MOPS Buffer for molecular biology
68078	Sisco Laboratories	100 ml	EUR 4.5
Description: Part B

Agarose High EEO for molecular biology
60645	Sisco Laboratories	25 Gms	EUR 13.8
Description: Part B

Jasmonic Acid for molecular biology, 95%
79238	Sisco Laboratories	25 Mg	EUR 120.9
Description: Part B

Protamine Sulfate for molecular biology, 90-110%
78349	Sisco Laboratories	1 Gms	EUR 22.5
Description: Part B

Oil Red O for molecular biology, 75%
23576	Sisco Laboratories	25 Gms	EUR 5.33
Description: Part B

Agarose Medium EEO for molecular biology
10423	Sisco Laboratories	10 Gms	EUR 6.75
Description: Part B

Sodium Chloride for molecular biology, 99.9%
33205	Sisco Laboratories	500 Gms	EUR 4.52
Description: Part A

Isopropanol (IPA) for molecular biology, 99.8%
38445	Sisco Laboratories	100 ml	EUR 1.71
Description: Part A

VOC Tetrahydrofuran Neat - 10MG
REVOC176N	Scientific Laboratory Supplies	10MG	EUR 52.73

Agarose Low Melting for molecular biology
32417	Sisco Laboratories	5 Gms	EUR 22.5
Description: Part B

Ammonium Acetate for molecular biology, 98%
37829	Sisco Laboratories	100 Gms	EUR 2.12
Description: Part A

Acetonitrile (ACN) for molecular biology, 99.9%
62006	Sisco Laboratories	250 ml	EUR 4.93
Description: Part A

Ethidium Bromide for molecular biology, 95%
93079	Sisco Laboratories	1 Gms	EUR 4.58
Description: Part A

3-(Chloromethyl)tetrahydrofuran
B423875	Toronto Research Chemicals	500mg	EUR 800
Description: 89181-22-6

Ammonium Chloride for molecular biology, 99.5%
16992	Sisco Laboratories	500 Gms	EUR 4.52
Description: Part A

Ammonium Sulphate for molecular biology, 99.5%
82126	Sisco Laboratories	250 Gms	EUR 4.93
Description: Part A

Potassium Acetate for molecular biology, 99.5%
96248	Sisco Laboratories	100 Gms	EUR 2.74
Description: Part A

Phenol Crystalline for molecular biology, 99.5%
17286	Sisco Laboratories	100 Gms	EUR 3.15
Description: Part A

Sodium Bicarbonate for molecular biology, 99.7%
36328	Sisco Laboratories	500 Gms	EUR 5.47
Description: Part A

Glycerol (Glycerine) for molecular biology, 99.5%
62417	Sisco Laboratories	100 ml	EUR 2.05
Description: Part A

Potassium Chloride for molecular biology, 99.5%
84984	Sisco Laboratories	500 Gms	EUR 6.16
Description: Part A

Dichloromethane (DCM) for molecular biology, 99.9%
41512	Sisco Laboratories	250 ml	EUR 3.22
Description: Part A

Acriflavine Neutral for molecular biology, 98%
42428	Sisco Laboratories	5 Gms	EUR 3.15
Description: Part B

2-Mercaptoethanol for molecular biology, 99%
83759	Sisco Laboratories	100 ml	EUR 5.27
Description: Part A

Artemether Tetrahydrofuran Acetate
A777415	Toronto Research Chemicals	250mg	EUR 244
Description: 181528-64-3

Dithioerythritol (DTE) for molecular biology, 99%
53384	Sisco Laboratories	1 Gms	EUR 9.53
Description: Part B

Tetrahydrofuran-2,5-dicarboxylic Acid
T293525	Toronto Research Chemicals	1g	EUR 167

Sodium chloride, suitable for molecular biology
GE0307	Glentham Life Sciences	1kg	EUR 41.33

Sodium chloride, suitable for molecular biology
GE0307-1	Glentham Life Sciences	1	EUR 45.2

L-Ascorbic Acid for molecular biology, 99.7%
14116	Sisco Laboratories	25 Gms	EUR 1.64
Description: Part A

HEPES Sodium Salt for molecular biology, 99%
32225	Sisco Laboratories	25 Gms	EUR 11.85
Description: Part B

meta-Topolin (mT) for molecular biology, 98%
68913	Sisco Laboratories	25 Mg	EUR 17.48
Description: Part B

Sucrose, GlenBiol, suitable for molecular biology
GC3201-1KG	Glentham Life Sciences	1 kg	EUR 90

2,5-Bishydroxymethyl Tetrahydrofuran
B446375	Toronto Research Chemicals	100mg	EUR 170
Description: 104-80-3

2-Methyl Tetrahydrofuran pure, 98%
99983	Sisco Laboratories	100 ml	EUR 2.26
Description: Part A

Glycogen ex. Oyster for molecular biology, 85%
49740	Sisco Laboratories	1 Gms	EUR 7.5
Description: Part B

2,5-Bis(aminomethyl)tetrahydrofuran
B404300	Toronto Research Chemicals	100mg	EUR 253
Description: 66918-21-6

VOC Std Tetrahydrofuran 2000ug/mL in MeOH - 1ML
REVOC176	Scientific Laboratory Supplies	1ML	EUR 74.91

2-(Tetrahydrofuran-3-yl)acetaldehyde
T293605	Toronto Research Chemicals	2.5g	EUR 1200
Description: 1072-94-2

Propidium Iodide (PI) for molecular biology, 95%
11195	Sisco Laboratories	10 Mg	EUR 17.63
Description: Part B

Acetic Acid Glacial for molecular biology, 99.9%
59788	Sisco Laboratories	100 ml	EUR 3.56
Description: Part A

Acrylamide 3x cryst. for molecular biology, 99.9%
61346	Sisco Laboratories	100 Gms	EUR 5.47
Description: Part A

Brilliant Blue G-250 for molecular biology
64222	Sisco Laboratories	5 Gms	EUR 4.65
Description: Part B

Brilliant Blue R-250 for molecular biology
93473	Sisco Laboratories	5 Gms	EUR 4.35
Description: Part B

D-Sorbitol Powder for molecular biology, 98%
99103	Sisco Laboratories	500 Gms	EUR 10.33
Description: Part A

Acriflavine Hydrochloride for molecular biology, 98.5%-105%
35188	Sisco Laboratories	5 Gms	EUR 4.05
Description: Part B

Tetrahydrofuran, GlenDry™, anhydrous
GS6029	Glentham Life Sciences	100ml	EUR 213.81

2-(4-Hydroxybutoxy)tetrahydrofuran
H819500	Toronto Research Chemicals	100mg	EUR 295
Description: 64001-06-5

Tetrahydrofuran, GlenDry™, anhydrous
GS6029-1	Glentham Life Sciences	1	EUR 121

Tetrahydrofuran, GlenDry™, anhydrous
GS6029-100	Glentham Life Sciences	100	EUR 66.4

Tetrahydrofuran, GlenDry™, anhydrous
GS6029-2500	Glentham Life Sciences	2500	EUR 223

Tetrahydrofuran, GlenDry™, anhydrous
GS6029-500	Glentham Life Sciences	500	EUR 88.7

Tetrahydrofuran Fentanyl Hydrochloride
T293476	Toronto Research Chemicals	10mg	EUR 1455

Tris Buffer Superior for molecular biology, 99.9%
37969	Sisco Laboratories	100 Gms	EUR 7.59
Description: Part A

Polysorbate 20 (Tween 20) for molecular biology
65296	Sisco Laboratories	100 Gms	EUR 10.81
Description: Part A

Tetrahydrofuran-2,5-dicarboxylic Acid (>80%)
T222765	Toronto Research Chemicals	1g	EUR 81
Description: 6338-43-8

Molecular Biology Grade Water for RT-PCR
ML065-1.5ML	EWC Diagnostics	1 unit	EUR 7.82
Description: Molecular Biology Grade Water for RT-PCR

10X TE Buffer pH-8.0 for molecular biology
51782	Sisco Laboratories	100 ml	EUR 9.45
Description: Part B

10X TAE Buffer pH-8.3 for molecular biology
71989	Sisco Laboratories	100 ml	EUR 4.43
Description: Part B

Tris Buffer AR, ACS for molecular biology, 99.9%
71033	Sisco Laboratories	100 Gms	EUR 6.02
Description: Part A

10X TBE Buffer pH-8.3 for molecular biology
83170	Sisco Laboratories	200 ml	EUR 4.95
Description: Part B

MES Monohydrate Buffer for molecular biology, 99%
26854	Sisco Laboratories	25 Gms	EUR 11.03
Description: Part B

Acrylamide 40% aq. solution for molecular biology
29787	Sisco Laboratories	250 ml	EUR 20.53
Description: Part A

2-((Tetrahydrofuran-2-yl)methoxy)phenol
T689455	Toronto Research Chemicals	10mg	EUR 201
Description: 41516-19-2

Glutathione Reduced (GSH) for molecular biology, 99.5%
11514	Sisco Laboratories	1 Gms	EUR 5.55
Description: Part B

DL-Dithiothreitol (DTT) for molecular biology, 98%
17315	Sisco Laboratories	1 Gms	EUR 5.18
Description: Part B

Cobalt(II) chloride-1,5-Tetrahydrofuran
GX7281	Glentham Life Sciences	10g	EUR 139.17

Cobalt(II) chloride-1,5-Tetrahydrofuran
GX7281-10	Glentham Life Sciences	10	EUR 88.9

Cobalt(II) chloride-1,5-Tetrahydrofuran
GX7281-25	Glentham Life Sciences	25	EUR 131.1

Sodium Acetate Anhydrous for molecular biology, 99%
22342	Sisco Laboratories	250 Gms	EUR 3.56
Description: Part A

Trifluoroacetic Acid (TFA) for molecular biology, 99.9%
40801	Sisco Laboratories	100 ml	EUR 22.92
Description: Part A

Ammonium Persulphate (APS) for molecular biology, 99%
65553	Sisco Laboratories	25 Gms	EUR 1.64
Description: Part A

Tetrabutylammonium Fluoride(1mol/l in Tetrahydrofuran)
08795-12	NACALAI TESQUE	25ML	EUR 21.7

(2S,3R,4R,5R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol
C419220	Toronto Research Chemicals	100mg	EUR 3000
Description: 1620758-32-8

(R)-2-(Tetrahydrofuran-3-Yl)Acetic-Acid
abx188023-10g	Abbexa	10 g	EUR 2932.8

Glutathione Oxidized (GSSG) for molecular biology, 99.5%
22151	Sisco Laboratories	250 Mg	EUR 22.5
Description: Part B

Cesium Chloride ultrapure for molecular biology, 99.9%
32355	Sisco Laboratories	25 Gms	EUR 18
Description: Part B

Cesium Sulphate extrapure for molecular biology, 99.9%
57455	Sisco Laboratories	10 Gms	EUR 7.5
Description: Part B

Guanidine Thiocyanate (GTC) for molecular biology, 99%
80272	Sisco Laboratories	100 Gms	EUR 5.47
Description: Part A

Fitness landscape can be used to describe the evolution of the potential trajectory of cancer, positive selection and mapping of neutral evolution of proto-oncogenes, tumor suppressor, and other functional elements. We also highlight the current challenges to implement these concepts and propose the research area, by incorporating these concepts, identify the mode of new therapies and in cancer susceptibility.